Bisphosphonates and osseointegration

Abstract

Bisphosphonates are a group of drugs commonly prescribed to treat patients with metabolic and oncological bone diseases. Moreover, cases of osteonecrosis in the mandible described, reporting this pathology in individuals using bisphosphonates following oral surgery procedures, including placement of dental implants. This review aims to give the clinician an insight into the current perspective of the relationship between bisphosphonates and dental implants. To this end, it is based on studies and reports of clinical cases carried out in humans in order to assess whether patients on bisphosphonates therapy or who have already undergone it are candidates to receive dental implants, and if they are submitted, what degree of risk to develop mandibular osteonecrosis. The current literature shows a considerable success rate among patients with bisphosphonates and who received dental implants; however, it is important that the dental surgeon take some precautions and alert the patient about the risks of implant loss, maxillary necrosis due to performed.